Murine Hox-1.11 homeobox gene structure and expression.
نویسندگان
چکیده
منابع مشابه
Murine Hox-1.11 homeobox gene structure and expression.
The Hox-1.11 gene encodes a protein 372 amino acid residues long that contains a conserved pentapeptide, a homeodomain, and an acidic region. The amino acid sequence of the homeodomain of Hox-1.11 is identical to that of Hox-2.8, and the N-terminal and C-terminal regions of Hox-1.11 are similar to those of human HOX2H, which is the equivalent of murine Hox-2.8. The Hox-1.11 gene was shown to re...
متن کاملStructure and expression of Hox-2.2, a murine homeobox-containing gene.
The Hox-2.2 gene is one of a cluster of homeobox-containing genes on mouse chromosome 11. A cDNA clone containing the Hox-2.2 homeobox has been isolated from an adult spinal cord library. Our analysis of the Hox-2.2 cDNA and genomic clones indicates that there are at least two oxons and one intron. The largest open reading frame includes the homeobox and codes for a 224 amino acid protein of mo...
متن کاملStructure and expression pattern of the murine Hox-3.2 gene.
The murine homeobox-containing gene Hox-3.2 is the most 5' member of the Hox-3 complex on chromosome 15 isolated to date. Conceptual translation of the longest ORF gives a protein of 260 amino acids lacking the conserved hexapeptide found in most homeobox genes. Northern analysis detects three transcripts of 1.5, 1.9 and 3.2 kb in day 9 to 15 p.c. embryos. As early as day 8.5 p.c., transcripts ...
متن کاملCoding sequence and expression of the homeobox gene Hox 1.3.
We have characterized Hox 1.3 (previously described as m2), a murine homeobox-containing gene, which is a member of the Hox 1 cluster located on chromosome 6. A cloned cDNA was isolated from an Okayama-Berg library generated from the chemically transformed cell line MB66 MCA ACL6. The protein sequence of 270 amino acids was deduced from the nucleotide sequence of an open reading frame containin...
متن کاملPrimary structure and embryonic expression pattern of the mouse Hox-4.3 homeobox gene.
We report the cloning, genomic localization, primary structure and developmental expression pattern of the novel mouse Hox-4.3 gene. This gene is located within the HOX-4(5) complex, at a position which classifies it as a member of the Hox-3.1 and -2.4 subfamily, the DNA and predicted protein sequences further confirmed this classification. Hox-4.3 has a primary structure characteristic of a Ho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1992
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.89.14.6280